Help us build the future of science education!

Substrate Games is reimagining how traditionally challenging health-focused science concepts are learned and taught. Using a game-based approach, we’re focused on building engaging, accessible, and effective products that students and their instructors genuinely love. Our initial focus is on expanding our organic chemistry prototype to tackle a notorious “weed out” course. With the support of both the National Institutes of Health and leading educational institutions, we are well-positioned to impact millions college students in a fast-growing $170B+ market.

No current openings.

Please check back later, or send a speculative application.


  • Help improve the learning experience for potentially millions of students.

  • Work with a nimble, mission-driven team.

  • Compensation package including salary, stock options, PTO, and 401k match.

  • Generous healthcare coverage including medical, dental, vision, life and long-term disability insurance.

  • Live where you choose and work remotely.

  • Opportunities for personal learning, professional development, and travel.